五一吃瓜官网

Research Impact:



Assistant Professor Dr Sami Ahmed Mohammed Ali Hamdoun

Assistant Professor

Academic Qualifications

  • PhD (Pharmacy)
  • Master in Molecular Medicine
  • Bachelor of Pharmacy

Areas of Interest
Anticancer agents
Antimicrobial agents
Molecular docking
Machine learning
Quantitative structure activity relationships
Drug discovery from natural products
Professional Bodies Membership

  • Americal Society of Microbiology
  • Sudan Medical Council (registered pharmacist)

Publications

1. Zhang, D., Hamdoun, S., Chen, R., Yang, L., Ip, C. K., Qu, Y., ... & Wong, V. K. W. (2021). Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry. Pharmacological research, 172, 105820.

2. Yang, L. J., Chen, R. H., Hamdoun, S., Coghi, P., Ng, J. P., Zhang, D. W., ... & Wong, V. K. W. (2021). Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding. Phytomedicine, 87, 153591.

3. Chen, R. H., Yang, L. J., Hamdoun, S., Chung, S. K., Lam, C. W. K., Zhang, K. X., ... & Wong, V. K. W. (2021). 1, 2, 3, 4, 6-Pentagalloyl glucose, a RBD-ACE2 binding inhibitor to prevent SARS-CoV-2 infection. Frontiers in pharmacology, 12, 634176.

4. Georgakopoulos, A., Kalampaliki, A. D., Gioti, K., Hamdoun, S., Giannopoulou, A. F., Efferth, T., ... & Kostakis, I. K. (2020). Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities. Arabian Journal of Chemistry, 13(11), 7953-7969.

5. Xu, S. W., Law, B. Y. K., Qu, S. L. Q., Hamdoun, S., Chen, J., Zhang, W., ... & Wong, V. K. W. (2020). SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells. Pharmacological Research, 153, 104660.

6. Wong, V. K. W., Qiu, C., Xu, S. W., Law, B. Y. K., Zeng, W., Wang, H., ... & Liu, L. (2019). Ca2+ signalling plays a role in celastrol‐mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats. British journal of pharmacology, 176(16), 2922-2944.

7. Abdelfatah, S., Berg, A., Huang, Q., Yang, L. J., Hamdoun, S., Klinger, A., ... & Efferth, T. (2019). MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate. Acta Pharmaceutica Sinica B, 9(5), 1021-1034.

8. Efferth, T., Banerjee, M., Abu-Darwish, M. S., Abdelfatah, S., B?ckers, M., Bhakta-Guha, D., ... & Paul, N. W. (2019). Biopiracy versus One-World Medicine–From colonial relicts to global collaborative concepts. Phytomedicine, 53, 319-331

9. Dawood, M., Hamdoun, S., & Efferth, T. (2018). Multifactorial modes of action of arsenic trioxide in cancer cells as analyzed by classical and network pharmacology. Frontiers in pharmacology, 9, 143.

10. Hamdoun, S., Fleischer, E., Klinger, A., & Efferth, T. (2017). Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells. Biochemical pharmacology, 146, 63-73

Awards

  • Turkish Scholarship for Short term research, Turkey (2022)
  • Science and Technology Development Fund postdoctoral research scholarship, Macau (2020)
  • DAAD scholarship for Ph.D. studies, Germany (2013)
  • Award of Excellence in academic performance, Institute of endemic diseases, Sudan (2007)